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- These enzymes are highly expressed in tumors as compared with normal tissues.
- This has been demonstrated across several cancer types and in normal tissues.
- They also kill fast-dividing normal tissues such as stomach or skin cells.
- Cancer-testes antigen MAGE-A3 is not known to be expressed in any normal tissues.
- FMNL2 expression is considerably higher in colorectal cancer tumors compared to normal tissue.